Evidence map›Paper›PMID 40821968›Full record

ArticleAsia-Pacific journal of oncology nursing2025

Self-perceived burden, fear of progression and psychological flexibility in cervical cancer survivors: A moderated network analysis.

Qihan Zhang, Furong Chen, Zhirui Xiao, Siyu Li, Yiguo Deng, M Tish Knobf, Jiaying Li, Zengjie Ye

Abstract read
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Article in Asia-Pacific journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Qihan ZhangSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Furong ChenSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Zhirui XiaoSchool of Nursing, University of South China, Hengyang, Hunan Province, China.
Siyu LiSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Yiguo DengSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
M Tish KnobfSchool of Nursing, Yale University, Orange, CT, United States.
Jiaying LiThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Zengjie YeSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Self-perceived burden (SPB) and Fear of progression (FoP) have been reported in people living with cancer and together may increase overall distress. Acceptance and Commitment Theory (ACT) posits that psychological flexibility (PF) may ameliorate the effects of the co-occurrence of these symptoms, yet empirical evidence is scarce. We examined the symptoms associated with SPB and FoP in women with cervical cancer and tested whether PF moderates the association. Methods: In a cross-sectional study, 307 cervical cancer survivors enrolled in the 2024 "Be Resilient to Cervical Cancer" (BRCC) program completed the Personalized Psychological Flexibility Index (PPFI), the Self-Perceived Burden Scale for Cancer Patients (SPBS-CP), and the Fear of Progression Questionnaire-Short Form (FoP-Q-SF). We constructed symptom-level networks to identify the strongest SPB-FoP connections, and explored the moderating role of PF using Johnson-Neyman analyses. Results: Among the 307 participants, the mean scores for PPFI were 59.13 (standard deviation [SD] ​= ​10.18), for FoP-Q-SF, 31.12 (SD ​= ​4.98), and for SPBS-CP, 48.18 (SD ​= ​17.12) indicating moderate levels of PF, fear of progression and SPB. Network analysis highlighted the "future worries"- "psychological burden" link as the strongest SPB-FoP link ( Conclusions: PF significantly moderates symptom-level associations between self-perceived burden on fear of progression among cervical cancer survivors. ACT-based interventions may attenuate such association to minimize patients' psychological distress.

Indexed as

Cervical cancerFear of progressionJohnson–Neyman analysisModerated network modelPsychological flexibilitySelf-perceived burden

Identifiers

PMID40821968
PMCPMC12355130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.