Evidence map›Paper›PMID 40821916›Full record

SynthesisFrontiers in global women's health2025

Evaluating treatment options for symptomatic uterine fibroids: a systematic review and meta-analysis of effectiveness, recovery, and long-term outcomes (MARIE WP1).

Elena Bedggood, Sun Jie, Snehal Ghosh, Vindya Pathiraja, Tharanga Mudalige, Nirmala Rathnayake, Heitor Cavalini, Om Kurmi, George Uchenna Eleje, Peter Phiri and 4 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in global women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elena Bedggood *Department of Applied Science, University of Birmingham, Birmingham, United Kingdom.
Sun Jie *Department of Statistics, Southern University of Science and Technology, Shenzhen, China.
Snehal Ghosh *Department of Applied Science, University of Birmingham, Birmingham, United Kingdom.
Vindya PathirajaFaculty of Allied Health Science, University of Ruhuna, Matara, Sri Lanka.
Tharanga MudaligeFaculty of Allied Health Science, University of Ruhuna, Matara, Sri Lanka.
Nirmala RathnayakeFaculty of Allied Health Science, University of Ruhuna, Matara, Sri Lanka.
Heitor CavaliniHampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, United Kingdom.
Om KurmiFaculty of Health and Life Science, Coventry University, Coventry, United Kingdom.
George Uchenna ElejeDepartment of Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.
Peter PhiriHampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, United Kingdom.
Paula BriggsDepartment of Gynaecology, Liverpool Womens Hospital NHS Foundation Trust, Liverpool, United Kingdom.
Jian Qing ShiDepartment of Statistics, Southern University of Science and Technology, Shenzhen, China.
Gayathri DelanerolleDepartment of Applied Science, University of Birmingham, Birmingham, United Kingdom.
Sohier ElneilInstitute of Womens Health, University College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Uterine fibroids can significantly impair the quality of life of women. While most fibroids remain asymptomatic, 25% of women diagnosed with uterine fibroids require medical intervention. Methods: A systematic review and meta-analysis protocol was developed and published in PROSPERO (CRD42022346251) to explore surgical treatment outcomes linked to uterine fibroids. Data was gathered using PubMed, Web of Science and ScienceDirect. The pooled data was analysed using the meta-package (version 8.0-1 and version 4.6-0) in R software (version 4.4.2). Results: Five studies met the eligibility criteria, and were further analysed to report quality of life, symptom severity and complications linked to surgery. Three studies ( Conclusion: Uterine artery embolisation and myomectomy result in comparable improvements in health-related quality of life although myomectomy appears to offer a greater reduction in symptom severity compared to uterine artery embolisation. These findings can assist clinicians and patients make improved shared decisions when selecting the most appropriate treatment for uterine fibroids. Improved research study designs and representation in sample need to be considered when conducting future research.

Indexed as

effectivenessmeta-analysissystematic reviewtreatment optionsuterine fibroids

Identifiers

PMID40821916
PMCPMC12350422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.