Evidence map›Paper›PMID 40821864›Full record

ReviewCurrent research in toxicology2025

Microplastics and nanoplastics in the ocular environment: Pathways, toxic effects, and future challenges.

Xiaotong Yu, Na Zhou, Qun Gao, Willie J G M Peijnenburg, Kun Yin, Lianzhen Li, Ye Wang

Abstract readReview
In one paragraph

Review in Current research in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaotong YuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Na ZhouCore Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, China.
Qun GaoCore Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, China.
Willie J G M PeijnenburgNational Institute for Public Health and the Environment, Center for Safety of Substances and Products, Bilthoven 3721 MA, The Netherlands.
Kun YinSchool of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Lianzhen LiCollege of Environmental Science and Engineering, Qingdao University, Qingdao 266071, China.
Ye WangCore Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266042, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro- and Nanoplastics (MNPs) have emerged as a significant environmental concern due to their widespread distribution and potential toxicity. While extensive research has explored the impacts of MNPs on various human organs, the eye, a particularly vulnerable tissue, has been relatively neglected. This review systematically examines the potential pathways through which MNPs can enter the eye, their accumulation in ocular tissues, and their potential toxic effects. We discuss the mechanisms by which MNPs may disrupt ocular health, including their ability to induce oxidative stress and inflammation, promote apoptosis, and cause genotoxicity and neurotoxicity. Additionally, we highlight the importance of future research on the effects of MNPs on the visual system, addressing current limitations and suggesting potential research directions. By enhancing our understanding of the risks posed by MNPs to ocular health, we can develop effective strategies to protect human vision and safeguard public health.

Indexed as

ChallengesMicroplasticsNanoplasticsPotential risksToxic effectsVisual system

Identifiers

PMID40821864
PMCPMC12357259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.