ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025
Relationship Between Type 1 Diabetes Mellitus and Dental Caries Status with Related Oral Health Indicators in Children.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to explore the relationship between type 1 diabetes mellitus (T1DM) and dental caries status along with related oral health indicators. Methods: A case-control study was conducted with a retrospective analysis of 40 diagnosed T1DM patients (patient group) and 40 age- and gender-matched healthy children (control group) treated at our hospital from 2020 to 2023. All participants underwent oral health assessments and relevant clinical examinations. By comparing the levels of related indicators between diabetic patients and healthy children, this study provides a scientific basis for prevention and treatment. Results: There was no significant difference in general baseline characteristics between the two groups (P>0.05). The levels of fasting blood glucose (FBG), 2-hour postprandial blood glucose (2h PBG), and glycated hemoglobin (HbA1c) were significantly higher in the patient group (P<0.05). The incidence of dental caries was significantly higher in the patient group (P<0.05). Additionally, the patient group had higher gingival bleeding index, plaque index, and probing depth (P<0.05). The salivary pH value in the patient group was also significantly higher (P<0.05). However, there was no significant difference in salivary immunoglobulin A (sIgA) and salivary immunoglobulin G (sIgG) between the groups (P>0.05). This study is limited by its small sample size (n=40 per group) and single-center retrospective design. Conclusion: Type 1 diabetes mellitus may alter saliva composition, while hyperglycemia can cause gingival inflammation and affect periodontal health. These changes may interfere with tooth mineralization, increasing caries risk in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.