Evidence map›Paper›PMID 40821723›Full record

ArticleDEN open2026

Endoscopic Ultrasonography-guided Variceal Therapy as Salvage Treatment for Rebleeding From Duodenal Varices Following Balloon-occluded Retrograde Transvenous Obliteration.

Sakue Masuda, Atsushi Irisawa, Soichiro Nakaya, Jun Kubota, Karen Kimura, Makomo Makazu, Kazuya Koizumi

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sakue MasudaDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0002-8127-0154
Atsushi IrisawaDepartment of Gastroenterology Dokkyo Medical University School of Medicine Tochigi Japan.
Soichiro NakayaDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.
Jun KubotaDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0002-8903-6207
Karen KimuraDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0002-3059-495X
Makomo MakazuDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.
Kazuya KoizumiDepartment of Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duodenal varices, though rare, are potentially life-threatening complications of portal hypertension. Management is challenging when balloon-occluded retrograde transvenous obliteration (BRTO) fails to achieve complete obliteration. Endoscopic ultrasonography-guided variceal therapy (EUS-VT) is effective for gastric varices, but reports of duodenal varices remain limited. We present a case of a 71-year-old woman with alcoholic liver cirrhosis and duodenal variceal bleeding. Initial hemostasis was achieved with endoscopic variceal ligation, followed by BRTO. However, rebleeding occurred due to incomplete obliteration caused by dual afferent veins. EUS-VT comprising n-butyl cyanoacrylate was performed as salvage therapy because of ascites and vascular complexity. Despite technical challenges, EUS-VT successfully obliterated the varices. Post-procedural computed tomography showed lipiodol migration into the portal system. No rebleeding or liver dysfunction occurred. Ascites worsened-likely because of BRTO and/or EUS-VT-but was manageable with low-dose diuretics. This case highlights EUS-VT as a feasible option after failed BRTO for duodenal varices. A meticulous technique is essential to preventing glue migration.

Indexed as

balloon‐occluded retrograde transvenous obliterationcyanoacrylate injectionduodenal varicesendoscopic ultrasoundvariceal bleeding

Identifiers

PMID40821723
PMCPMC12352126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.