Evidence map›Paper›PMID 40821407›Full record

ArticleWorld journal of clinical cases2025

Leaving no stone unturned: Impact of appendicolith and characteristics on long-term recurrence after non-operative appendicitis.

Amram Kupietzky, Yehonatan Bar-Moshe, Nofar Lavie, Moriya Drayer Lichtman, Roi Dover, Eyal Yonathan Juster, Ata Maden, Haggi Mazeh, Ido Mizrahi

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Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amram KupietzkyDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel. amramkupietzky@gmail.com.
Yehonatan Bar-MosheDepartment of Radiology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Nofar LavieFaculty of Medicine, Hebrew University of Jerusalem, Jerusalem 12000, Israel.
Moriya Drayer LichtmanDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Roi DoverDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Eyal Yonathan JusterDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Ata MadenDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Haggi MazehDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.
Ido MizrahiDepartment of Surgery, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91240, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-operative management (NOM) for uncomplicated acute appendicitis (AA) has been gaining popularity in recent years. One of the major concerns with NOM is the recurrence rate of AA following NOM.

aimTo investigate the impact of the presence of an appendicolith and its specific characteristics on the recurrence rate of AA following NOM.

methodsA retrospective analysis identified all patients treated with NOM for AA, at our institute between 2016 and 2024. Patients with an appendicolith on imaging were identified and their course and outcomes were compared with patients who were treated with NOM without an appendicolith. The primary outcome was defined as a recurrence of AA.

resultsDuring the study period, 797 patients were treated with NOM for AA. Their mean age was 25.4 years ± 14.4 years, and 45.4% were females. Only 68 patients (8.5%) had an appendicolith identified on imaging. Patients with an appendicolith had a larger appendix diameter (10.2 mm ± 4 mm

conclusionThis study demonstrates that patients with appendicoliths have a shorter time to recurrence after NOM of AA, but do not experience higher overall recurrence rates.

Indexed as

Acute appendicitisAppendicolithConservative managementNon-operative managementRecurrent acute appendicitis

Identifiers

PMID40821407
PMCPMC12188775

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