Evidence map›Paper›PMID 40821401›Full record

ArticleWorld journal of clinical cases2025

Convergence of diabetic ketoacidosis, acute pancreatitis, and malaria: A case report.

Koffi Isidore Kouame, Paterne Michael N'kan Mobio, Judith Kouesseu Bouh, Jean Kouassi Konan, Theodore Klinnan Coulibaly, Cyrille Wallamitien Toure, Lauraine Armande Assoh Diebi, Jose Ndjassipli Homawoo Kouakou, Bable Essuy Koffi, Paul Yapo Yapo

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Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Koffi Isidore KouameUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire. kouamedocinterne@gmail.com.
Paterne Michael N'kan MobioUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Judith Kouesseu BouhUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Jean Kouassi KonanUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Theodore Klinnan CoulibalyUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Cyrille Wallamitien ToureUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Lauraine Armande Assoh DiebiUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Jose Ndjassipli Homawoo KouakouUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Bable Essuy KoffiUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.
Paul Yapo YapoUnit of Training and Research in Medical Sciences, Félix Houphouët Boigny University, Abidjan 22BP582, Cote d'Ivoire.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 1 diabetes is an autoimmune disease leading to insulin deficiency, and it is mainly diagnosed in young adults. One of the major acute complications of type 1 diabetes is diabetic ketoacidosis (DKA), which is a metabolic emergency that can be triggered by stress, infection, or poor blood glucose control. The association of DKA with conditions such as acute pancreatitis and malaria is rare and therefore represents a major diagnostic and therapeutic challenge. CASE SUMMARY: A 20-year-old female was admitted to the emergency room for abdominal pelvic pain, fever, asthenia, polyuria, and polydipsia with a progressive deterioration of her state of consciousness. At admission, she was in a mild coma (Glasgow score: 9), had a fever of 38.5 °C, and had hyperglycemia (6 g/dL). The tests revealed severe DKA, hypertriglyceridemia, hyperamylasemia, and hyperlipasemia as well as malaria parasite density. The computed tomography scan confirmed acute stage E pancreatitis. The diagnosis was that of inaugural ketoacidosis of type 1 diabetes unbalanced by pancreatitis and malaria. Treatment included insulin therapy, rehydration, and antimalarial and analgesic treatment. After 10 days, the outcome was favorable with a normalization of the blood sugar, and an endocrine follow-up was recommend.

conclusionRapid and multidisciplinary management of DKA, pancreatitis, and malaria led to a favorable and stable prognosis.

Indexed as

Acute pancreatitisCase reportDiabetic ketoacidosisHypertriglyceridemiaMalariaType 1 diabetes

Identifiers

PMID40821401
PMCPMC12188763

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