ArticleInternational medical case reports journal2025
Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report.
Article in International medical case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
Ameloblastoma, a locally aggressive benign odontogenic tumor, represents about 1% of jaw tumors. While typically affecting adults aged 30-60, this case highlights its occurrence in a 17-year-old. Incidence varies globally, with lower rates in non-African populations (around 0.5 per million annually) compared to higher prevalence in Nigeria and South Africa, where Black populations show increased susceptibility. Limited epidemiological data from sub-Saharan Africa, including Uganda, likely underestimates the burden due to underreporting in rural areas with poor healthcare access. A 17-year-old female of the Azande tribe, Bantu ethnicity, presented with a four-year history of a massive, painless right mandibular swelling causing significant facial asymmetry. Examination revealed a large mass (13.8 x 11.5 x 11 cm). A CT scan indicated a unilocular cystic lesion. Histopathology confirmed ameloblastoma with follicular and plexiform patterns. The patient underwent a right total hemi-mandibulectomy, and the excised tumor (19 x 16×10 cm) was classified as an intraluminal unicystic ameloblastoma. This case emphasizes the presentation of a giant unicystic ameloblastoma in a young individual from sub-Saharan Africa, a demographic often underreported. The delayed presentation and substantial tumor size underscore diagnostic and management challenges in resource-limited settings. This report highlights the need for enhanced awareness and improved healthcare access for timely intervention in these populations. Vigilant long-term follow-up is essential due to the tumor's recurrence potential.
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