Evidence map›Paper›PMID 40821353›Full record

ArticleCureus2025

Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular Risk.

Selin Unal, Keston Rattan, Mir Sulayman Khan, Roy Wang, Omar Amro, Inna Bukharovich

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Selin UnalInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Keston RattanInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Mir Sulayman KhanInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Roy WangInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Omar AmroInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Inna BukharovichCardiology, Kings County Hospital Center, Brooklyn, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wellens syndrome is a rare variant of acute coronary syndrome (ACS) that often heralds an impending large anterior wall myocardial infarction. We present the case of a young male with no traditional coronary artery disease (CAD) risk factors. Despite only minimally elevated troponin levels, the patient's smoking history, serial electrocardiogram (ECG) changes, and the emerging evidence linking cannabis use to cardiovascular risk contributed to the timely diagnosis of Wellens syndrome. Although cannabis is increasingly accepted for medical and recreational use, growing concerns have been raised about its potential adverse cardiovascular effects. This case highlights the importance of early identification and prompt intervention. In Wellens syndrome, a conservative approach is associated with poor outcomes, making the decision to proceed with an invasive strategy critical. Understanding the association between cannabis use and myocardial infarction may shape future medical management as cannabis consumption continues to rise.

Indexed as

cad: coronary artery diseasecannabis usecritical care cardiologyecg interpretationwellens syndrome

Identifiers

PMID40821353
PMCPMC12357741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.