Evidence map›Paper›PMID 40821339›Full record

ReviewCureus2025

From Cells to Strands: A Systematic Review Comparing Exosome Therapy, Platelet-Rich Plasma, and Minoxidil for Androgenetic Alopecia Treatment.

Rajah Darwish, Marina Zakhary, Kaleigh Wingate, Noura Ayoubi, Faisal Ghafoor, Bushra Ejaz

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Exosomes in precision dermatology: From biomarkers to targeted therapeutics in personalized care.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajah DarwishDepartment of Dermatology, Florida State University College of Medicine, Tallahassee, USA.
Marina ZakharyDepartment of Psychiatry, Florida State University College of Medicine, Tallahassee, USA.
Kaleigh WingateDepartment of Psychiatry, Florida State University College of Medicine, Tallahassee, USA.
Noura AyoubiDepartment of Dermatology, Brandon Regional Hospital / University of South Florida (USF) Health Morsani College of Medicine, Brandon, USA.
Faisal GhafoorDepartment of Pain Management, JQZ by Qalandars Clinics, Lahore, PAK.
Bushra EjazDepartment of Public Health Sciences, Hussain Memorial Hospital, Lahore, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgenetic alopecia (AGA) is a prevalent condition that significantly impacts psychological well-being and quality of life. Traditional therapies such as minoxidil and platelet-rich plasma (PRP) offer varying degrees of success, while exosome therapy has recently emerged as a potential alternative. This review compares the effectiveness, safety, and patient-centered outcomes of exosome therapy, PRP, and minoxidil in the management of AGA. The findings suggest that exosome therapy shows the most promising results in terms of hair regrowth and safety, followed by PRP, which offers moderate benefits. Minoxidil remains the most accessible treatment, though with more limited effectiveness and the need for continuous use. Overall, exosome therapy appears to hold the greatest potential for long-term improvement. Further research is needed to guide clinical decision-making and optimize treatment outcomes.

Indexed as

alopeciaexosome therapyhair regrowthminoxidilprp therapy

Identifiers

PMID40821339
PMCPMC12351504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.