Evidence map›Paper›PMID 40821327›Full record

ArticleCureus2025

Recurrent Thrombotic Thrombocytopenic Purpura Associated With Helicobacter pylori: More Than a Gut Feeling.

Esperance M Madera, Keon J Sargon, Domonick K Gordon, Alexandra Zodo, Gerarda Corneille, Devon Cole, Gaurav Paul, Ariel S Mandelblum, Daniel Han, Musa Ayyad and 1 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Esperance M MaderaInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Keon J SargonInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Domonick K GordonInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Alexandra ZodoInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Gerarda CorneilleInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Devon ColeInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Gaurav PaulInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Ariel S MandelblumInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Daniel HanInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Musa AyyadInternal Medicine, Mount Sinai Hospital, Chicago, USA.
Kulsum FarooqiInternal Medicine, Mount Sinai Hospital, Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening hematologic disorder characterized by severe ADAMTS13 deficiency, leading to uncontrolled platelet aggregation, microvascular thrombosis, and multi-organ dysfunction. Although the pathogenesis of immune-mediated TTP (iTTP) is primarily autoimmune, infectious agents, including

Indexed as

adamts13 deficiencyhelicobacter pylorimicroangiopathic hemolytic anemia (maha)platelet aggregationthrombotic thrombocytopenic purpura (ttp)

Identifiers

PMID40821327
PMCPMC12354924

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.