ArticleCureus2025
Acute Spontaneous Spinal Epidural Hematoma in a Patient on a Direct Oral Anticoagulant (DOAC): A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Spontaneous Spinal Epidural Haematoma Associated With Direct Oral Anticoagulants: A Descriptive Systematic Review.Cureus · 2026Review
- Article
- [Radiological imaging of spinal trauma in special situations].Radiologie (Heidelberg, Germany) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute spontaneous spinal epidural hematoma (SSEH) is a rare but serious condition that can mimic stroke or carotid artery dissection (CAD), potentially leading to misdiagnosis and inappropriate therapy. We report the case of a 75-year-old male with atrial fibrillation on Edoxaban who awoke with neck pain and, approximately 80 minutes later, developed sudden right-sided weakness. Neurological examination showed right upper limb (RUL) weakness (3/5 proximally, 0/5 distally), right lower limb (RLL) paralysis (0/5), hypotonia, but intact sensation, with a National Institutes of Health Stroke Scale (NIHSS) score of 6 - findings that supported conservative management in the absence of progressive deterioration. Initial CT head and CT angiogram were unremarkable, ruling out intracranial hemorrhage and carotid dissection. Aortic dissection was also excluded by CT aortogram. Although uncontrolled hypertension or other acute risk factors were not identified (blood pressure (BP) 157/81 mmHg), chronic anticoagulation likely contributed to SSEH. Cervical spine magnetic resonance imaging (MRI) performed on day 6 revealed a C3-C5 epidural hematoma compressing the cord. Neurosurgical consultation recommended conservative management due to improving strength and absence of worsening symptoms. Follow-up MRI at six weeks confirmed complete hematoma resolution with residual mild myelopathy. At discharge, after a 10-day hospital stay, the patient's neurological function had improved to 4/5 strength in the RUL and 3/5 in the RLL, and he was transferred for rehabilitation. This case underscores the importance of considering SSEH in anticoagulated patients with acute neck pain and hemiparesis, even when initial imaging for stroke or CAD is negative. Timely MRI and a multidisciplinary approach are crucial to avoid misdiagnosis and optimize outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.