Evidence map›Paper›PMID 40821277›Full record

ArticleCureus2025

Prevalence and Detection of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus (hVISA) Among Clinical Isolates: A Comparative Evaluation of Screening Methods.

Aditi Agarwal, Lipika Singhal, Ivneet Kour, Parakriti Gupta, Navreet Kaur, Dipanshu Vasesi, Varsha Gupta

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aditi AgarwalMicrobiology, Geetanjali Medical College and Hospital, Udaipur, IND.
Lipika SinghalMicrobiology, Government Medical College & Hospital, Sector 32, Chandigarh, IND.
Ivneet KourMicrobiology, Government Medical College & Hospital, Sector 32, Chandigarh, IND.
Parakriti GuptaMicrobiology, Government Medical College & Hospital, Sector 32, Chandigarh, IND.
Navreet KaurMicrobiology, Government Medical College & Hospital, Sector 32, Chandigarh, IND.
Dipanshu VasesiMicrobiology, Maharishi Markandeshwar Medical College and Hospital, Solan, IND.
Varsha GuptaMicrobiology, Government Medical College & Hospital, Sector 32, Chandigarh, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsA prospective, observational study was conducted over 1.5 years, analyzing 102 non-duplicate clinical isolates of

resultsAmong the 102 isolates, 49.02% were MRSA, and all were susceptible to vancomycin based on MIC values. However, 8.82% exhibited the hVISA phenotype out of the total

conclusionThe detection of hVISA is critical for optimizing treatment strategies and preventing therapeutic failures. The study suggests that BHIV4 screening can serve as an effective method for initial hVISA detection. Continuous surveillance and judicious antimicrobial use are essential to curb the emergence of resistance.

Indexed as

antimicrobial resistanceheteroresistant staphylococcus aureus (hvisa)mrsa (methicillin-resistant staphylococcus aureus)staphylococcus aureusvancomycin-intermediate staphylococcus aureus (visa)

Identifiers

PMID40821277
PMCPMC12356989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.