ArticleCureus2025
Spontaneous Regression of Multiple Osteochondromas in a Patient With Hereditary Multiple Exostoses: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hereditary multiple exostoses (HME) is an autosomal dominant disorder characterized by the development of multiple osteochondromas, primarily near the metaphyses of long bones. We report a case of HME in which multiple symptomatic lesions showed spontaneous regression. The patient was an 11-year-old boy with osteochondromas involving both distal femurs and the left forearm. At age 13, he developed discomfort and pain during squatting and forearm rotation, and radiographs revealed progressive enlargement of the lesions. Given that the physes remained open, we chose a conservative approach. At age 15, the symptomatic lesions had regressed significantly, and his symptoms resolved without surgical intervention. This case demonstrates that even symptomatic lesions in HME may regress spontaneously during growth, supporting the value of conservative management before physeal closure. Surgical decisions should be guided by the clinical course of the lesion rather than its morphology or transient symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.