Evidence map›Paper›PMID 40821223›Full record

ArticleCureus2025

Degenerative Changes in the Disc, Facet Joint, and Paraspinal Muscle After Adolescent Idiopathic Scoliosis Surgery: A Five-Year MRI-Based Follow-Up.

Takaaki Uto, Noriaki Yokogawa, Satoshi Kato, Takaki Shimizu, Satoshi Nagatani, Masafumi Kawai, Yuji Ishino, Kazuhiro Nanpo, Satoru Demura

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Takaaki UtoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Noriaki YokogawaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Satoshi KatoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Takaki ShimizuDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Satoshi NagataniDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Masafumi KawaiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Yuji IshinoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Kazuhiro NanpoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.
Satoru DemuraDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives This study aimed to comprehensively assess degenerative changes in the intervertebral disc, facet joint, and paraspinal muscle after adolescent idiopathic scoliosis surgery and to evaluate clinical outcomes at a five-year follow-up using magnetic resonance imaging (MRI). We hypothesized that the pattern of degeneration would differ based on the distal level of fusion. Materials and methods We retrospectively reviewed patients with adolescent idiopathic scoliosis who underwent surgery between 2006 and 2015. The patients were divided into two groups based on the lowest instrumented vertebra (LIV): a proximal LIV group (L2 or above) and a distal LIV group (L3 or below). Degeneration was evaluated using MRI with the Pfirrmann and Fujiwara scoring systems. Fatty infiltration of paraspinal muscles was specifically assessed at the L5/S1 disc level, distal to the surgical field, using the Goutallier scoring system. Clinical outcomes were measured using the Scoliosis Research Society-22 (SRS-22) Patient Outcome Questionnaire. Statistical comparisons were performed using the Mann-Whitney U test and Wilcoxon signed-rank test. Results The proximal LIV group comprised 21 patients, while the distal LIV group had 19 patients. Postoperatively, six of 40 patients (15%) exhibited progression of disc degeneration in mobile segments, with no significant difference between groups. The proximal LIV group showed significant progression of facet joint degeneration up to three levels below the fusion, whereas the distal LIV group showed similar changes up to two levels. However, the distal LIV group demonstrated greater overall facet degeneration. Paraspinal muscle degeneration at the L5/S1 level was observed in 19 of 40 patients (47.5%), with a higher prevalence in the distal LIV group (73.7% vs. 23.8%). Clinical outcomes were satisfactory and did not differ significantly between the groups. Conclusions At the five-year mark, this study suggests an association between a more proximal LIV (L2 or above) and less facet joint and paraspinal muscle degeneration in patients undergoing fusion for adolescent idiopathic scoliosis. However, these preliminary radiological findings did not correlate with clinical symptoms, which remained satisfactory in both groups. These results should be interpreted with caution, and extended follow-up is necessary to determine the long-term clinical significance of these degenerative changes.

Indexed as

adjacent segment degenerationadolescent idiopathic scoliosis (ais)facet joint degenerationivdd (intervertebral disc degeneration)long-term follow-up after orthopedic surgerylowest instrumented vertebramri evaluationparaspinal muscle atrophyspinal fusion surgerysrs-22

Identifiers

PMID40821223
PMCPMC12356694

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