Evidence map›Paper›PMID 40821209›Full record

ArticleCureus2025

Ultrasound-Guided Peripheral Nerve Block for Emergency Below-Knee Amputation in a High-Risk Patient With Coagulopathy: A Case Report.

Shashank Krishnakumar, Vinod Krishnagopal, Raj Murugan, Roshni Iyer

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shashank KrishnakumarAnaesthesiology, Apollo Hospitals, Chennai, IND.
Vinod KrishnagopalAnaesthesiology, Sree Balaji Medical College and Hospital, Chennai, IND.
Raj MuruganAnaesthesiology, Sree Balaji Medical College and Hospital, Chennai, IND.
Roshni IyerAnaesthesiology, Parvathy Hospitals, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergency below-knee amputation (BKA) in patients with significant comorbidities and coagulopathy presents formidable anesthetic challenges, as a central neuraxial blockade and general anesthesia are frequently contraindicated. We report the case of a 57-year-old female patient with uncontrolled diabetes mellitus, chronic kidney disease, coronary artery disease, and an elevated international normalized ratio (INR) of 1.6, necessitating urgent BKA for a septic diabetic foot ulcer. Ultrasound-guided peripheral nerve blocks (PNBs, popliteal sciatic and femoral) have been successfully employed to achieve effective intraoperative anesthesia and postoperative analgesia without bleeding complications or hemodynamic instability. This case underscores the safety and efficacy of ultrasound-guided PNBs as the preferred anesthetic strategy in high-risk patients with coagulopathy, offering a safer alternative to conventional methods and minimizing perioperative morbidity.

Indexed as

anticoagulationbelow-knee amputationdiabetic footultrasound-guided peripheral nerve blockultrasound-guided regional anesthesia

Identifiers

PMID40821209
PMCPMC12352365

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.