ArticleCureus2025
A Rectal Mass That Deceived: Solitary Plasmacytoma Masquerading as Mantle Cell Lymphoma With Subsequent Progression to Multiple Myeloma.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
Solitary extramedullary plasmacytomas (SEPs) are rare plasma cell tumors, particularly when located in the gastrointestinal tract. Misdiagnosis may occur due to overlapping histological and immunophenotypic features with other hematologic malignancies, such as mantle cell lymphoma (MCL). We present the case of a 63-year-old female patient initially diagnosed with MCL based on rectal mass biopsy, who underwent lymphoma-directed therapy. Surgical excision and further histopathological evaluation revised the diagnosis to SEP. Over time, the patient developed serum monoclonal gammopathy and progressed to multiple myeloma (MM). This case highlights the diagnostic pitfalls of rectal lymphoid lesions, the value of surgical pathology, and the potential for SEPs to evolve into systemic plasma cell neoplasia.
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