Evidence map›Paper›PMID 40821171›Full record

ArticleCureus2025

Idiopathic Intracranial Hypertension Without Papilledema: A Case Emphasizing the Diagnostic Value of Optic Nerve Sheath Ultrasound.

Asif Mahbub Swapnil, Md Samiul Islam, Latif Rahman, Khalil Fatih Ali Khalil, Nasrul Nijam

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asif Mahbub SwapnilAcute Medicine, University Hospitals of Leicester National Health Service (NHS) Trust, Leicester, GBR.
Md Samiul IslamMedicine, University Hospitals of Leicester National Health Service (NHS) Trust, Leicester, GBR.
Latif RahmanAcute Medicine, Leicester Royal Infirmary, Leicester, GBR.
Khalil Fatih Ali KhalilNeurology, University Hospitals of Leicester National Health Service (NHS) Trust, Leicester, GBR.
Nasrul NijamNeurology, University Hospitals of Leicester National Health Service (NHS) Trust, Leicester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 45-year-old woman with obesity who presented with some features of idiopathic intracranial hypertension (IIH), including postural headache and pulsatile tinnitus, but notably without papilledema. Initial investigations, including optical coherence tomography (OCT) of the optic nerve and computed tomography (CT) of the head, were unremarkable, resulting in a delay in diagnosis. Due to persistent symptoms, optic nerve sheath diameter (ONSD) assessment via ultrasound was performed, revealing bilateral dilation. Subsequent magnetic resonance imaging (MRI) identified an empty sella and distension of the optic nerve sheaths. A lumbar puncture confirmed an elevated opening pressure of 30 cm H₂O, establishing the diagnosis of IIH. This case illustrates the diagnostic challenges of IIH in the absence of papilledema and emphasizes the emerging utility of optic nerve sheath ultrasound as a non-invasive tool to aid in the early detection of raised intracranial pressure.

Indexed as

cerebrospinal fluid (csf)elevated intracranial pressureoptic nerve sheathpapilloedemaultrasound imaging

Identifiers

PMID40821171
PMCPMC12357743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.