ArticleCureus2025
Arterial Spin Labelling Perfusion Changes in Persistent Migrainous Aura Without Infarction.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a common disorder characterized by recurrent, usually unilateral, pulsatile headaches often accompanied by nausea, vomiting, photophobia, phonophobia, and fatigue. Visual aura is the most common of all aura symptoms in migraine patients. The aura and headache phases of migraine are caused by intracranial vasoconstriction and extracranial vasodilation, respectively. Migrainous aura without infarction refers to migraine aura symptoms that persist for an extended period of one week or longer without any evidence of infarction on imaging. Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging technique used to quantitatively assess cerebral blood flow. It can be used to track perfusion changes over the migraine cycle. This case report highlights the utility of ASL as a non-invasive tool to detect reversible perfusion changes in persistent migrainous aura, aiding in differentiating it from ischemic events, offering insights into underlying pathophysiology, such as cortical spreading depression, and informing more accurate clinical management.
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