Evidence map›Paper›PMID 40821151›Full record

ReviewCureus2025

Evolving Strategies in Amblyopia Management: From Traditional Therapies to Cutting-Edge Innovations.

Mina H Younan, Youssef T Youssef, Unaiza Erum, Muhammad Talal Nasir, Mohamed Ismaeil, Minar Aziz, Viola N Fawzy, Nadine Mourad, Mohamed Ismaiel, Mohamed Sherif Ali Ahmed and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mina H YounanDepartment of General Surgery, Hull University Teaching Hospitals NHS Trust, Hull, GBR.
Youssef T YoussefDepartment of General Surgery, Mansoura University Faculty of Medicine, Mansoura, EGY.
Unaiza ErumDepartment of General Surgery, Foundation University Medical College, Islamabad, PAK.
Muhammad Talal NasirDepartment of General Surgery, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Mohamed IsmaeilDepartment of General Surgery, Prince Charles Hospital, Merthyr Tydfil, GBR.
Minar AzizDepartment of General Surgery, Aneurin Bevan University Health Board, Newport, GBR.
Viola N FawzyDepartment of Physiology, Suez Canal University, Ismailia, EGY.
Nadine MouradDepartment of Ophthalmology, Alexandria University Hospitals, Alexandria, EGY.
Mohamed IsmaielDepartment of General Surgery, Royal Victoria Infirmary Hospital, Newcastle upon Tyne, GBR.
Mohamed Sherif Ali AhmedDepartment of Ophthalmology, Mansoura University, Mansoura, EGY.
Lydia MeladDepartment of Ophthalmology, Beni-Suef University, Beni Suef, EGY.
Momen AbdelglilDepartment of Pediatric Surgery, Mansoura University Children's Hospital, Mansoura, EGY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amblyopia, commonly referred to as "lazy eye," is a prevalent visual disorder affecting children and, in some cases, adults. Traditional treatments, including occlusion therapy and pharmacological approaches, have demonstrated efficacy but also face limitations related to adherence, age dependency, and recurrence rates. This narrative review explores evolving strategies in amblyopia management, from conventional therapies to emerging innovations. Dichoptic therapy, which leverages binocular visual stimulation, represents a paradigm shift by directly addressing neural suppression and improving stereopsis. Technological advancements, such as virtual reality (VR), AI, and eye-tracking technologies, have further revolutionized treatment approaches, enhancing compliance and enabling personalized care. Additionally, recent research in neuroplasticity has opened new avenues for treating adult amblyopia, challenging previous assumptions about its irreversibility. Despite these advancements, challenges persist in treatment standardization, accessibility, and long-term efficacy.

Indexed as

amblyopianeuroplasticityophthalmologypediatric ophthalmologyvision therapy

Identifiers

PMID40821151
PMCPMC12352807

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.