ReviewGenes & diseases2025
The regulatory role and mechanism of energy metabolism and immune response in head and neck cancer.
Review in Genes & diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Targeting metabolic reprogramming in HPV-associated oral squamous cell carcinoma: current advances, challenges, and clinical prospects.Journal of molecular histology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Head and neck cancer, which includes cancers of the mouth, larynx, and pharynx, is one of the six most common cancers worldwide. Common risk factors include smoking, excessive alcohol consumption, betel nut chewing, and viruses such as HPV and EBV. Tumor cells often exhibit distinct metabolic characteristics compared with normal cells, highlighting a key area for potential intervention. By targeting these metabolic pathways, it is possible to influence tumor initiation and progression. Therefore, this review primarily describes the alterations in glucose metabolism, amino acid metabolism, lipid metabolism, and the immune system in head and neck cancer patients and discusses potential treatment strategies to advance the understanding of head and neck cancer and the development of therapeutic drugs for it.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.