ArticleAmerican journal of translational research2025
Efficacy of esketamine in alleviating emergence delirium and agitation in pediatric patients undergoing adenotonsillectomy under general anesthesia.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the effect of esketamine on emergence delirium (ED) and emergence agitation (EA) in pediatric patients under general anesthesia.
methodsThis retrospective study included 94 pediatric patients who underwent adenotonsillectomy under general anesthesia at General Hospital of Ningxia Medical University from January 2023 to October 2024. The patients were divided into three groups according to different anesthesia protocols they received: Group A (n=30, esketamine 0.5 mg/kg), Group B (n=32, esketamine 0.75 mg/kg), and Group C (n=32, fentanyl 2 µg/kg). Hemodynamic values, surgical indicators, pstoperative pain and agitation (the Face, Legs, Activity, Cry, and Consolability (FLACC) scale face, legs, activity, Cry, and consolability (FLACC) scale and the Pediatric Anesthesia Emergence Delirium (PAED) scale), the incidence of EA and ED, and perioperative adverse events were compared across the groups. Factors associated with EA and ED occurrence were analyzed.
resultsGroups A and B exhibited significantly shorter time to spontaneous respiration, extubation, and awakening than Group C (
conclusionCompared to fentanyl, esketamine, particularly at a dose of 0.75 mg/kg, eenhanced perioperative hemodynamic stability, reduced postoperative ED and EA incidence, and demonstrated a favorable safety profile in pediatric adenotonsillectomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.