ArticleAmerican journal of translational research2025
Orthodontic treatment in patients with chronic periodontitis significantly improves periodontal health.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate alterations in inflammatory biomarkers and systemic homeostasis in patients with chronic periodontitis following orthodontic intervention.
methodsClinical data of 80 chronic periodontitis patients, treated between April 2019 and April 2024, were retrospectively analyzed. Patients were stratified into two groups: a control group (n=32) receiving standard periodontal therapy and a research group (n=48) undergoing additional orthodontic treatment. Comprehensive clinical evaluations were conducted, including assessments of therapeutic outcomes, periodontal parameters (tooth mobility [TM], gingival index [GI], papillary bleeding index [PBI], and probing depth [PD]), inflammatory biomarkers (interleukin [IL]-2 and IL-8), oral health-related quality of life (Oral Health Impact Profile-14 [OHIP-14]), and masticatory efficiency. Additionally, plaque control efficacy was evaluated using the modified plaque index (mPLI) and modified sulcus bleeding index (mSBI), while gingival architecture was assessed by the papilla index score (PIS).
resultsCompared to the control group, the research group demonstrated significantly superior outcomes, including higher overall treatment efficacy, improved masticatory function, and greater patient satisfaction (P<0.05). Additionally, post-treatment assessments revealed significantly lower values in the research group for TM, GI, PBI, PD, mPLI, mSBI, PIS, IL-2, IL-8, and OHIP-14 scores.
conclusionsOrthodontic therapy in chronic periodontitis patients not only improves periodontal health but also reduces systemic inflammatory responses, thereby promoting the restoration of oral-systemic homeostasis.
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