ArticleAmerican journal of translational research2025
Association between nutritional risk and clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo explore the relationship between nutritional risk and clinical outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease COPD (AECOPD).
methodsThe medical records of 220 AECOPD patients hospitalized between June 2022 and June 2024 were retrospectively analyzed. The patients were categorized into two groups based on their Nutritional Risk Index (NRI): high-risk ([NRI] < 92) group and low-risk (NRI ≥ 92) group. Clinical outcomes assessed included albumin levels, arterial blood gas parameters, frequency of exacerbations, in-hospital mortality, length of hospital stays, readmission rates, and health-related quality of life (HRQoL). Pulmonary function recovery, including forced expiratory volume in one second (FEV
resultsCompared to the low-risk group, patients in the high-risk group exhibited significantly lower albumin levels (P = 0.007), increased frequency of exacerbations (P = 0.005), higher in-hospital mortality (P = 0.004), prolonged hospital stays (P = 0.001), and elevated readmission rates (P = 0.002). High-risk patients also reported significantly lower physical function (PF) and mental health scores. After treatment, improvements in FEV
conclusionNutritional risk is closely associated with the severity, prognosis, and recurrence of AECOPD. These findings underscore the importance of nutritional assessment and intervention in the management of hospitalized AECOPD patients.
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