ArticleAmerican journal of translational research2025
Off pump method of coronary artery bypass grafting enhances therapeutic efficacy and safety in elderly coronary heart disease patients.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo compare the therapeutic effects of off-pump versus conventional coronary artery bypass grafting (CABG) in elderly coronary heart disease (CHD) patients.
methodsThis retrospective study analyzed 98 elderly CHD patients (47 conventional CABG, 51 off-pump CABG) treated between April 2019 and March 2021. Outcomes included intraoperative and postoperative indicators (distal anastomoses, mechanical ventilation time, hospital stay), graft patency, left ventricular function (LVEF, LVEDD), cardiac biomarkers (cTnI, CK, CK-MB), complication rates, 3-month quality of life (QoL), and long-term major adverse cardiovascular and cerebrovascular events (MACCE).
resultsThe two groups had similar distal anastomoses and graft patency rates (P>0.05). However, the off-pump group had shorter mechanical ventilation time and hospital stay than the conventional group (both P<0.05). LVEF and LVEDD showed no significant differences between the two group pre- and post-surgery. Cardiac biomarkers (cTnI, CK, CK-MB) increased postoperatively in both groups but were significantly lower in the off-pump group (P<0.05). The off-pump group had fewer complications, better QoL scores in social, mental, emotional, and overall health, and lower long-term MACCE incidence than the conventional group (all P<0.05).
conclusionOff-pump CABG reduces surgical trauma, shortens recovery time, lowers complication rates, and improves QoL compared to conventional CABG, making it a preferable option for elderly CHD patients.
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