ArticleAmerican journal of translational research2025
Hypothermia therapy enhances cognitive and motor recovery in patients with traumatic brain injury: a 6-month retrospective cohort study.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the efficacy of therapeutic hypothermia in enhancing cognitive and motor outcomes six months post-TBI.
methodsA retrospective cohort analysis was conducted on data from the Medical Information Mart for Intensive Care (MIMIC) database. A total of 259 TBI patients were divided into a Routine group (n = 135) and a Hypothermia Therapy group (n = 124). The hypothermia group received core temperature reduction to 33-35°C for 3-5 days. Cognitive and motor functions were assessed using the Functional Independence Measure (FIM), Fugl-Meyer Motor Assessment (FMA), and Glasgow Coma Scale (GCS) at baseline and six months post-treatment. Patients' satisfaction was also evaluated.
resultsAfter six months of treatment, the hypothermia group showed significantly higher FIM motor scores, and FIM cognitive scores than the routine group (P < 0.01). A higher proportion of patients in the hypothermia group achieved mild impairment on the FMA assessment than in the routine group (P = 0.003). The hypothermia group demonstrated better consciousness levels (P = 0.006) and reported significantly higher patient satisfaction rate (P = 0.004).
conclusionHypothermia therapy significantly improved cognitive and motor recovery in TBI patients, enhanced consciousness levels, and increased patient satisfaction rate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.