Evidence map›Paper›PMID 40821047›Full record

ArticleAmerican journal of translational research2025

Regular nasal irrigation modulates nasal microbiota and improves symptoms in allergic rhinitis patients: a retrospective study.

Hong Wu, Xiaoping Pu

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hong WuDepartment of Otolaryngology, Xishan People's Hospital of Wuxi Wuxi 214100, Jiangsu, China.
Xiaoping PuDepartment of Otolaryngology, Xishan People's Hospital of Wuxi Wuxi 214100, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effects of regular nasal irrigation on nasal microbiota and symptom improvement in allergic rhinitis patients.

methodsThis retrospective study involved 202 allergic rhinitis patients. Participants were divided into a conventional treatment group (mometasone furoate spray and loratadine) and an observation group (nasal irrigation added to the conventional regimen). Nasal microbiota diversity, biofilm formation, nasal symptoms, and quality of life were assessed before and after a one month of treatment. A correlation analysis was performed to evaluate the relationships between nasal irrigation and clinical outcomes.

resultsThe nasal irrigation group exhibited significant reductions in nasal microbiota richness (P = 0.014), biofilm-forming

conclusionsRegular nasal irrigation serves as an effective adjunctive treatment for allergic rhinitis by modulating nasal microbiota, alleviating symptoms, and enhancing quality of life.

Indexed as

Allergic rhinitisbiofilm formationnasal irrigationnasal microbiotaquality of lifesymptom improvement

Identifiers

PMID40821047
PMCPMC12351610

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.