Evidence map›Paper›PMID 40820716›Full record

ArticleJournal of cardiovascular electrophysiology2025

A Novel Predictive Score to Identify the Necessity for Epicardial Ventricular Tachycardia Ablation: EPI-VT-Score.

Moneeb Khalaph, Denise Guckel, Nadica Trajkovska, Maxim Didenko, Mustapha El Hamriti, Martin Braun, Guram Imnadze, Philip Lucas, Thomas Fink, Vanessa Sciacca and 8 more

Abstract readValidation Study
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

18 authors.

Moneeb KhalaphDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0009-0004-2454-1335
Denise GuckelDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0000-0003-1470-7157
Nadica TrajkovskaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Maxim DidenkoDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Mustapha El HamritiClinic for Cardiology/Electrophysiology, GZO-Spital Wetzikon, Zürich, Suisse.
Martin BraunDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Guram ImnadzeMedical Clinic A - Rhythmology, University Hospital Ruppin-Brandenburg, Neuruppin, Germany.
Philip LucasDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Thomas FinkDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Vanessa SciaccaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Sebastian BeyerDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Yuri BocchiniDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Alessandro GuareschiDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Arseniy GoncharovDepartment of General and Interventional Cardiology/Angiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Kawa MohemedDepartment of General and Interventional Cardiology/Angiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Volker RudolphDepartment of General and Interventional Cardiology/Angiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Christian SohnsDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0000-0003-0490-5862
Philipp SommerDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0000-0002-3037-8704

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundEpicardial ventricular tachycardia (VT) ablation is a therapeutic option for drug-refractory VT, particularly when endocardial ablation fails or is inadequate. However, accurately identifying patients who will benefit most from an epicardial approach remains challenging due to its higher procedure-related risks.

objectiveThis study aimed to develop and validate a predictive scoring model - EPI-VT-Score - to identify patients likely to benefit from epicardial VT ablation.

methodsWe retrospectively analyzed data from 138 patients (mean age 64.9 ± 11.3 years, 89.9% male) who underwent VT ablation between 2018 and 2024. Four predictors - underlying cardiomyopathy, left ventricular ejection fraction (LVEF), number of prior VT ablations, and VT-QRS interval - were identified and incorporated into the EPI-VT-Score, which ranges from 4 to 12 points. Score performance was assessed using area under curve (AUC).

resultsAmong 138 patients, 51 (37.0%) underwent epicardial ablation. The EPI-VT-Score accurately predicted epicardial ablation necessity with an AUC of 0.990 (95% CI, 0.978-1.000). A score ≥ 8 identified epicardial need with 92.2% sensitivity and 100% specificity. Patients scoring < 8 were effectively managed with endocardial-only ablation.

conclusionThe EPI-VT-Score can be a clinical support to evaluate preprocedural necessity for epicardial access and the complexity of the procedure to improves procedural outcomes as well as minimize unnecessary procedural risks.

Indexed as

Catheter AblationDecision Support TechniquesPericardiumTachycardia, VentricularAction PotentialsAgedClinical Decision-MakingFemaleHeart RateHumansMaleMiddle AgedPatient SelectionPredictive Value of TestsReproducibility of ResultsRetrospective Studiesepicardial VT ablationEPI‐VT‐Scoreindication of VT ablationVT ablationVT‐score

Identifiers

PMID40820716
PMCPMC12614129

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