Evidence map›Paper›PMID 40820686›Full record

ArticleHuman vaccines & immunotherapeutics2025

Service delivery costs of vaccination at health facilities in Guangzhou, China.

Chunhuan Zhang, Zeyu Liu, Yong Huang, Zhiwei Zheng, Wenji Wang, Zhoubin Zhang

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunhuan ZhangDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.
Zeyu LiuDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.
Yong HuangDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.
Zhiwei ZhengDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.
Wenji WangDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.
Zhoubin ZhangDepartment of Vaccination Management and Guidance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regular, comprehensive, and effective cost analyses of immunization services are essential for evaluating whether current policy subsidies are suitable for these services. However, such studies are relatively limited in China. This study is the first comprehensive investigation of the costs of immunization services in Guangzhou City. Through stratified random sampling, we selected 84 vaccination clinics covering 11 administrative districts, including routine, adult, and rabies vaccination clinics. Investigate the vaccination service costs of various types of outpatient clinics. The cost investigation adopts the top - down full cost method to examine the labor costs, operating costs, and fixed - asset depreciation costs of each vaccination unit. In addition, it is need to clarify that vaccine procurement costs were not included in the scope of this cost analysis. Key findings revealed that the costs per dose (293.70 CNY,$41.66) and per person (433.96 CNY,$61.55) were significantly higher at adult vaccination clinics than routine vaccination clinics (per dose: 64.88 CNY($9.20); per person: 153.66 CNY($21.80)) and rabies vaccination clinics (per dose: 252.15 CNY($35.77); per person: 867.13 CNY($123.00)). For all surveyed vaccination units, labor costs accounted for the largest proportion of total costs (75.02%), and was followed by operational costs (19.67%) and fixed assets (5.31%). Univariate and multivariate regression analyses identified several factors influencing service costs. An increase in the standard number of staff per week was associated with higher vaccination service costs. Factors associated with lower vaccination service costs included clinics that were privately operated, served larger population sizes, offered services on more days per week, or had moderate to large vaccination areas. This comprehensive analysis provides valuable insights for optimizing resource allocation, improving vaccination accessibility across the life course, and informing policy development to support sustainable immunization programs.

Indexed as

Health Care CostsHealth FacilitiesImmunization ProgramsVaccinationAdultChinaCosts and Cost AnalysisHumansRabies VaccinesRabies Vaccinescost analysisGuangzhou cityinvestigationresource allocationVaccination service

Identifiers

PMID40820686
PMCPMC12363536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.