Evidence map›Paper›PMID 40820574›Full record

Trial reportJournal of diabetes investigation2025

Effects of Tai Chi Chuan on balance function in adults 60 years or older with type 2 diabetes and mild cognitive impairment in China: A secondary analysis of a multi-center randomized clinical trial.

Jiawei Qin, Jia Huang, Jue Liu, Yannan Chen, Jia Luo, Liyuan Tao, Zhizhen Liu, Weilin Liu, Ying Xu, Shengxiang Liang and 6 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Optimal type and dose of exercise to improve cognitive function in healthy and pre-sarcopenic older adults: a bayesian network meta-analysis of randomized controlled trials.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jiawei QinCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.ORCID https://orcid.org/0000-0001-6561-7333
Jia HuangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Jue LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.ORCID https://orcid.org/0000-0002-1938-9365
Yannan ChenCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Jia LuoCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Liyuan TaoResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China.
Zhizhen LiuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Weilin LiuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Ying XuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Shengxiang LiangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Cong ChenCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Qiang TangSecond Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Haerbin, Heilongjiang, China.
Zhuhong ChenChina Academy of Chinese Medical Sciences, Xiyuan Hospital, Beijing, China.
Shangjie ChenThe Second Affiliated Hospital of Shenzhen University, Shenzhen, China.
Lidian ChenCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Jing TaoCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.

Funding

Ministry of Science and Technology of the People's Republic of China 2019YFC1710301
6 · The paper itself

Abstract

aimsTo investigate the effect of Tai Chi Chuan on balance function in adults 60 years or older with type 2 diabetes and mild cognitive impairment (MCI) in China. MATERIALS AND

methodsThis was a three-arm, parallel-group, randomized controlled trial with concealed allocation, assessor blinding, intention-to-treat (ITT), and per-protocol (PP) analysis. 328 adults 60 years or older, with a diagnosis of both type 2 diabetes and MCI, were randomly allocated into Tai Chi Chuan group, fitness walking group, and control group. All three groups were provided with a 30-min diabetes self-management education session, once every 4 weeks, for 24 weeks. In addition, the Tai Chi Chuan group received 24-form simplified Tai Chi Chuan. The fitness walking group received fitness walking training. Both Tai Chi Chuan and fitness walking groups took the training for 60 min/session, three times/week, for 24 weeks in a supervised setting. After completing the 24-week interventions, the participants were encouraged to continue exercise until the 36-week follow-up evaluation. The outcomes were time up and go (TUG) assessments, one leg standing test (OLST), functional reach test (FRT), grip strength, 5 time sit to stand test (5STS), modified fall efficacy scale (MFES), and falls data at baseline, 24 weeks, and 36 weeks follow-up.

resultsAt 36 weeks, the Tai Chi Chuan group was significantly more effective in decreasing the TUG-cognitive-motor (mean difference, -0.72; 95% CI -1.37 to -0.06), OLST (eyes-closed, right leg) (mean difference, 1.02; 95% CI 0.24-1.80), FRT (mean difference, 2.00; 95% CI 0.57-3.42), 5STS (mean difference, -0.66; 95% CI -1.28 to -0.04), and MFES (mean difference, 0.36; 95% CI 0.15-0.56) compared with the fitness walking group. The Tai Chi Chuan group showed significantly fewer total falls during 36-week experimental period compared with the fitness walking group. PP analysis demonstrated similar results as the ITT analysis.

conclusionsAmong the older adults with type 2 diabetes and MCI, Tai Chi Chuan was more effective than fitness walking and control at improving balance function and reducing fall risk.

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2Postural BalanceTai JiAgedChinaFemaleFollow-Up StudiesHumansMaleMiddle AgedMild cognitive impairmentTai Chi ChuanType 2 diabetes mellitus

Identifiers

PMID40820574
PMCPMC12578669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.