ArticleActa radiologica (Stockholm, Sweden : 1987)2025
ADC values compared to tumor grade and Ki-67 proliferation index detected by a digital image analysis program in meningiomas.
Article in Acta radiologica (Stockholm, Sweden : 1987), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Time-dependent prognostic value of automated Ki67 assessment and its integration with molecular risk profiling in WHO grade 2 meningioma.Acta neuropathologica communications · 2026Article
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3 authors.
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Abstract
BackgroundMeningiomas are the most common extra-axial tumors of the central nervous system, and accurate preoperative assessment of their histological grade is essential for effective treatment planning.PurposeTo investigate the relationship between the apparent diffusion coefficient (ADC) sequence, histopathological grade, and Ki-67 proliferation index for radiologically identifying meningiomas with poor prognosis.Material and MethodsThe study included 90 patients with histopathologically confirmed meningioma between March 2019 and February 2021. The Ki-67 proliferation index was assessed using an image analysis program. Retrospectively, ADC maps and diffusion-weighted imaging (DWI) were reviewed. An oval-shaped region of interest was placed over the lesion's solid component and the normal-appearing white matter in the opposite hemisphere. Each patient's ADC ratio (ADC meningioma/ADC normal-appearing white matter) was calculated. The relationship between ADC and Ki-67 proliferation index was investigated, and ADC values of benign and atypical meningiomas were compared. Independent sample
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