ReviewScience progress
Primary adrenal CD56-negative extranodal NK/T-cell lymphoma: Case report and literature review.
Review in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- EBV-positive CD8 + peripheral T-cell lymphoma in the post-transplant setting: case report and review of the literature.Journal of hematopathology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary adrenal extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is exceptionally rare, and it remains unclear whether this subtype of ENKTL exhibits distinct clinicopathological features. This case report describes a later 30s female patient who presented with 6 months of back pain. 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) revealed a hypermetabolic left adrenal mass. Histopathology revealed diffuse atypical lymphocytes with necrosis and vascular invasion. Immunohistochemical analysis demonstrated tumor cell positivity for CD3, CD2, CD8, TIA-1, and granzyme B, while being negative for CD5, CD4, CD56, CD20, Pax-5, CD30 and keratin, with a Ki-67 proliferation index of approximately 80%. Chromogenic in situ hybridization showed strong and uniform nuclear positivity of Epstein-Barr virus-encoded RNA (EBER) in the neoplastic population. T-cell receptor rearrangement (TR-γ) was in germline configuration. The final diagnosis of primary adrenal CD56-negative extranodal NK/T-cell lymphoma was confirmed. Chemotherapy was initiated immediately. But she died within 4 months because of disease progression. Primary adrenal ENKTL appears to be exceedingly rare and might portend a particularly poor prognosis. CD56 negativity and advanced stage could potentially represent key prognostic determinants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.