ArticleEuropean geriatric medicine2026
Association between sarcopenia and hypercoagulability in elderly patients with chronic obstructive pulmonary disease.
Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- 101 machine learning algorithms for predicting mortality in critically ill patients with spinal cord injury and sarcopenia: a multi-database study.BMC medical informatics and decision making · 2026Observational
- Integrating Machine Learning for Early COPD Prediction in Lung Cancer Patients: A Focus on Systemic Coagulation-Inflammation Index.International journal of chronic obstructive pulmonary disease · 2026Article
- Research Progress of Sarcopenia Index in Chronic Obstructive Pulmonary Disease: A Review.Cureus · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBlood hypercoagulability is associated with poor prognosis in elderly patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to explore whether sarcopenia, a common disease among the elderly, could promote the hypercoagulable state in such patients.
methodsElderly patients with stable-phase COPD were divided into the sarcopenia group (n = 192) and the non-sarcopenia group (n = 264). Sarcopenia was diagnosed according to the criteria for risk assessment, muscle mass measurement, muscle strength evaluation, and muscle function assessment. All patients were followed up for 18 months, and the acute exacerbation of COPD was recorded. The characteristics of COPD, coagulation function, and potential confounding factors during the stable and acute exacerbation phases were collected. Multivariate logistic or linear regression was used for data analysis.
resultsCompared with the non-sarcopenia group, the levels of PLT and AT-III in patients of the sarcopenia group were significantly lower, while the levels of PAR, PT, APTT, FIB, and D-dimer were significantly higher during both the stable phase and the acute exacerbation phase of COPD. More importantly, compared with the non-sarcopenia group, the deterioration amplitudes of most coagulation indicators in patients of the sarcopenia group were significantly greater during the process of COPD developing from the stable phase to the acute exacerbation phase.
conclusionThere is a significant correlation between sarcopenia and blood hypercoagulability in elderly patients with COPD. Sarcopenia seemingly has the potential to be a risk factor for the blood hypercoagulable state in such patients, but further verification is still needed.
Indexed as
Identifiers
40820192What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.