ArticleScientific reports2025
High prevalence of penicillin-resistant group B Streptococcus among pregnant women in Northwest Ethiopia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Methicillin and inducible clindamycin resistance in Gram-positive cocci among GeneXpert-positive pulmonary tuberculosis patients and apparently healthy individuals in Northwest Ethiopia.BMC microbiology · 2026Article
- Penicillin-Binding Proteins inAntibiotics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Group B Streptococcus (GBS) is a normal constituent of the female genital and gastrointestinal flora but remains a leading cause of perinatal bacterial infections, including endometritis, bacteremia, chorioamnionitis, and urinary tract infections in pregnant women. In Ethiopia, reported GBS colonization rates among pregnant women range from 7.2 to 25.5%. This study aimed to determine the prevalence, antimicrobial susceptibility patterns, and associated factors of GBS colonization among pregnant women attending antenatal care (ANC) at Debre Markos Comprehensive Specialized Hospital, Northwest Ethiopia. An institutional-based cross-sectional study was conducted from March 1 to May 30, 2021. After obtaining written consent, sociodemographic data were collected using a structured questionnaire, conveniently. A total of 210 recto-vaginal swabs were collected, inoculated into Todd-Hewitt broth, and sub-cultured on 5% blood agar. Antimicrobial susceptibility testing was performed using the disk diffusion method following Clinical and Laboratory Standards Institute 2020 guidelines. Data were entered and cleaned in Epi Data version 3.1 and analyzed using SPSS version 20. Binary logistic regression identified associations between variables, with a P value ≤ 0.05 considered statistically significant. The overall GBS colonization was 13.3% (28/210). Married women had significantly higher odds of colonization (AOR 5.774; 95% CI 1.074-31.03; P = 0.041), while those with a history of abortion had lower odds (AOR 0.294; 95% CI 0.102-0.850; P = 0.024). Most isolates were susceptible to chloramphenicol (96.4%). Resistance rates were highest for erythromycin (71.4%) and penicillin (67.9%), followed by ampicillin (64.3%), azithromycin (46.4%), vancomycin (46.4%), and ceftriaxone (32.1%). Half of the isolates were multidrug-resistant. GBS colonization among pregnant women in the study area warrants clinical attention due to its associated high antibiotic resistance. Being married and abortion had statistically significant associations with colonization. Therefore, clinicians could implement routine GBS screening for all pregnant women attending ANC to reduce GBS colonization. Routine GBS screening may help reduce neonatal sepsis, pneumonia, and meningitis by guiding timely intrapartum antibiotic prophylaxis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.