Evidence map›Paper›PMID 40820098›Full record

Trial reportScientific reports2025

Randomized clinical trial on effectiveness of modified Akinosi technique in mandibular molars with symptomatic irreversible pulpitis during endodontic therapy.

Aarti Bohora, Rohan Bhambar, Dheeraj Kalra, Vinay Sharma, Padmaja Sirsat, Anuj Bhardwaj, Alexander Maniangat Luke, Krishna Prasad Shetty, Ajinkya M Pawar, Mohmed Isaqali Karobari

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aarti BohoraDepartment of Conservative Dentistry and Endodontics, SMBT Institute of Dental Sciences and Research, Nandi Hills, Nasik, India.
Rohan BhambarConsulting Oral and Maxillofacial Surgeon, Nasik, India.
Dheeraj KalraDepartment of Public Health Dentistry, SMBT Institute of Dental Sciences and Research, Nandi Hills, Nasik, India.
Vinay SharmaDepartment of Conservative Dentistry and Endodontics, SMBT Institute of Dental Sciences and Research, Nandi Hills, Nasik, India.
Padmaja SirsatDepartment of Conservative Dentistry and Endodontics, SMBT Institute of Dental Sciences and Research, Nandi Hills, Nasik, India.
Anuj BhardwajDepartment of Conservative Dentistry and Endodontics, College of Dental Sciences and Hospital, Rau, Indore, India.
Alexander Maniangat LukeDepartment of Clinical Science, College of Dentistry, Ajman University, Al-Jruf, P.O. Box 346, Ajman, United Arab Emirates.
Krishna Prasad ShettyDepartment of Clinical Science, College of Dentistry, Ajman University, Al-Jruf, P.O. Box 346, Ajman, United Arab Emirates.
Ajinkya M PawarDepartment of Conservative Dentistry and Endodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India.
Mohmed Isaqali KarobariDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600077, India. dr.isaq@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study is to investigate the effectiveness of the modified Akinosi technique [MAT] in endodontic management of mandibular molars with symptomatic irreversible pulpitis, and to compare it with the standard inferior alveolar nerve block for effective pulpal anesthesia. A total of 80 clinically healthy patients of both genders, between 16 and 65 years, diagnosed with symptomatic irreversible pulpitis in mandibular first and second molars were included in the study. The subjects were divided into two groups. Group A received nerve block and pulpal anesthesia through Inferior Alveolar Nerve Block technique, while Group B received nerve block through MAT with 2% lignocaine containing 1:200,000 adrenaline. All endodontic treatments were performed in a single visit. We evaluated the presence of pain during various phases of endodontic treatment with Visual Analog Scale. The pain level was registered at the end of the following phases of the endodontic treatment: 1. During access cavity preparation; 2. While determining working length for all the root canals; 3. During cleaning and shaping of root canals. In Group B, 80% of patients reported no pain, as compared to 51% in Group A. MAT is an effective method for achieving pulpal anesthesia in endodontic treatment of symptomatic irreversible pulpitis.

Indexed as

MolarNerve BlockPulpitisRoot Canal TherapyAdolescentAdultAgedFemaleHumansLidocaineMaleMandibleMiddle AgedPain MeasurementTreatment OutcomeYoung AdultLidocaineEndodontic treatmentMandibular anesthesiaModified Akinosi techniquePain controlPulpal anesthesia

Identifiers

PMID40820098
PMCPMC12358531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.