Evidence map›Paper›PMID 40819974›Full record

ArticleBritish journal of anaesthesia2025

Local adoption of norepinephrine as the first-line vasopressor in major noncardiac surgery: impact of a pragmatic clinical trial on real-world practice.

Christopher Ansay, Shweta A Chawla, Nicholas Fong, Rachel Lin, Joyce M Chang, Elizabeth L Whitlock, Rishi P Kothari, Matthieu Legrand, Michael P Bokoch

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christopher AnsayDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Shweta A ChawlaDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Nicholas FongDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Rachel LinDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Joyce M ChangDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Elizabeth L WhitlockDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Rishi P KothariDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA; Department of Anesthesiology & Perioperative Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Matthieu LegrandDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA.
Michael P BokochDepartment of Anesthesiology and Perioperative Care, University of California, San Francisco, CA, USA. Electronic address: Michael.Bokoch@ucsf.edu.

Funding

The choice of vasopressor to prevent postoperative acute kidney injury after major non-cardiac surgery: a multicenter pragmatic cluster cross-over randomized trial (the VEGA-2 trial)R01DK139484 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SACHIN KHETERPAL, Matthieu Legrand · 2024 to 2026
$2.0M
NIDDK NIH HHS R01 DK139484
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute kidney injuryarterial pressurecatecholamineshypotensionnorepinephrineorgan injuryphenylephrine

Identifiers

PMID40819974
PMCPMC12674007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.