Evidence map›Paper›PMID 40819865›Full record

ArticleBMJ open2025

Lung and cardiac ultrasound for respiratory distress in the elderly: study protocol of the LUC REED stepped-wedge cluster randomised trial.

Frederic Balen, Manon Hebrard, Clément Delmas, Xavier Dubucs, Elise Noel-Savina, Nadège Costa, Jason Shourick, LUC REED investigators, and the LUC REED investigators

Erratum issued Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06807983 (Impact of a Management Strategy for Acute Dyspnea in Elderly Subjects Based on the Use of Lung and Cardiac Ultrasonography), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06807983 narecruitingnot on this map

Impact of a Management Strategy for Acute Dyspnea in Elderly Subjects Based on the Use of Lung and Cardiac Ultrasonography

TypeinterventionalSponsorUniversity Hospital, ToulouseRan2025 to 2027Enrolled504ConditionsDyspnea, Respiratory Distress SyndromeArmsdiagnostic strategy based on lung and cardiac ultrasonography
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Frederic BalenEmergency Department, CHU Toulouse, Toulouse, France fred.balen@gmail.com.ORCID http://orcid.org/0000-0002-4340-7391
Manon HebrardEmergency Department, CHU Toulouse, Toulouse, France.
Clément DelmasIntensive Cardiac Care Unit, CHU Toulouse Pôle cardiovasculaire et métabolique, Toulouse, France.
Xavier DubucsCERPOP, Toulouse, France.
Elise Noel-SavinaDepartment of Pneumology, CHU Toulouse, Toulouse, France.
Nadège CostaCERPOP, Toulouse, France.ORCID http://orcid.org/0000-0002-1185-3960
Jason ShourickCERPOP, Toulouse, France.
LUC REED investigators
and the LUC REED investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDyspnea is a common chief complaint leading to emergency department (ED) visits. Multiple conditions may cause or be associated with dyspnoea, including bacterial pneumonia, acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (COPD) or asthma and pulmonary embolism. Each of these diagnoses has a specific treatment recommended by international guidelines. Inappropriate treatment in the ED is more frequent among elderly patients and is independently associated with in-hospital mortality. Point-of-care ultrasound is immediately available at the bedside. Lung and cardiac ultrasound (LuCUS) offers excellent diagnostic accuracy for bacterial pneumonia, AHF and COPD exacerbations, even in elderly patients. The primary objective of the LUC REED trial is to evaluate the impact of a LuCUS-guided strategy versus standard care on reducing inappropriate treatment of dyspnoea in elderly ED patients. METHODS AND ANALYSIS: The LUC REED trial is a prospective, interventional, multicentre, stepped-wedge randomised controlled trial designed to assess the superiority of a LuCUS-guided strategy over standard care in ensuring treatment appropriateness for dyspnoea in elderly ED patients. The study will include 504 patients over 2 years. Patients aged >65 years presenting with acute dyspnoea and signs of severity (respiratory rate ≥22 or SpO ETHICS AND DISSEMINATION: Ethics final approval was obtained from the Institutional Review Board of France-Est IV on 4 April 2025 (2024-A01678-39). Results will be published in peer-reviewed international journals. TRIAL REGISTRATION NUMBER: NCT06807983.

Indexed as

DyspneaEchocardiographyHeartLungAgedEmergency Service, HospitalEquivalence Trials as TopicFemaleHeart FailureHumansMaleMulticenter Studies as TopicPneumonia, BacterialProspective StudiesPulmonary Disease, Chronic ObstructiveRandomized Controlled Trials as TopicEmergency Service, HospitalFrail ElderlyRespiratory Distress SyndromeULTRASONOGRAPHY

Identifiers

PMID40819865
PMCPMC12359426

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.