ReviewCurrent opinion in neurobiology2025
Gut-brain communication in Drosophila melanogaster.
Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Article
- Credit to the Fruit Fly: How the Tiny Insect Lights Up Our Understanding of Human Disease.Insects · 2026Review
- Gut distension evokes rapid neural dynamics in vagal and hindbrain populations of larval zebrafish.iScience · 2026Article
- Connectomic mapping of pharyngeal and gut sensory circuits in adultbioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Over the past decades, significant advancements have transformed our understanding of the gut-brain circuits in Drosophila melanogaster. In this review, we explore how mapping these circuits and signaling pathways has deepened our knowledge of the neural and hormonal pathways that regulate nutrient preference, feeding behavior, metabolism, and other homeostatic behaviors in flies. We summarize the recent breakthroughs in gut-brain communication and highlight how these advancements have provided valuable insights into the complex relationship between the gut and the brain. Finally, we emphasize the importance of Drosophila as a model system for investigating gut-brain communication. Insights from fly research not only enhance our understanding of fundamental gut-brain biology but also provide promising avenues for identifying molecular targets for therapeutic strategies in humans for gastrointestinal and metabolic disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.