Evidence map›Paper›PMID 40819346›Full record

SynthesisAnnals of medicine2025

Incidence and risk factors of acute kidney injury after abdominal surgery: a systematic review and meta-analysis.

Jian Liu, Shi-Hui Lin, Yi-Si Zhao, Ren-Jie Luo, Zheng-Tao Zhang, Liu-Yang Wang, Ke Xie, Jing Fan, Mu Zhang, Yu-Sen Chai and 2 more

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07638306 (Dynamic Internal Jugular Vein Assessment During Anesthesia Induction as a Predictor of Hemodynamic Instability and Postoperative Outcomes), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07638306 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Dynamic Internal Jugular Vein Assessment During Anesthesia Induction as a Predictor of Hemodynamic Instability and Postoperative Outcomes

Typeobservational_patient_registrySponsorTîrgu Mureș Emergency Clinical County Hospital, RomaniaRan2026 to 2027Enrolled150ConditionsIntraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With PropofolArmsInternal Jugular Vein Ultrasound Assesment
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A Dynamic Online Nomogram for Predicting Postoperative Acute Kidney Injury After Sleeve Gastrectomy.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jian LiuDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Shi-Hui LinDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Yi-Si ZhaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Ren-Jie LuoDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Zheng-Tao ZhangDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Liu-Yang WangDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Ke XieDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Jing FanDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Mu ZhangDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Yu-Sen ChaiPulmonary Engineering Group, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden at Technische Universität Dresden, Dresden, Germany.
Hong TangDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Fang XuDepartment of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.ORCID 0000-0001-8201-1595

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the incidence of acute kidney injury (AKI) following abdominal surgery, assess its outcome associations, and identify factors associated with postoperative AKI development.

methodsWe performed a systematic search of PubMed, Embase, and Cochrane Database of Systematic Reviews, from January 2004, to December 2024. We included studies reporting AKI based on consensus criteria (RIFLE, AKIN, or KDIGO) in adult abdominal surgery patients.

resultsA total of 162 studies (675361 patients) were included. The pooled AKI incidence was 16% (95% CI: 14-17%), with significant variation by surgical procedure. Meta-analysis showed AKI was significantly associated with increased short-term mortality (risk ratio [RR], 6.46; 95% CI: 4.63-9.00) and long-term mortality (RR, 6.36; 95% CI: 3.32-12.16). Mortality risk demonstrated stage-dependent increase, with RR of 2.74 (95%CI: 1.77-4.24), 8.01 (95%CI: 3.18-20.18), and 15.73 (95%CI: 5.52-44.81) for AKI stages 1, 2, and 3, respectively. AKI was associated with prolonged hospital stay (weighted mean difference 4.72 days; 95%CI: 3.43-6.02), also showeing stage-dependent increase of 5.03, 11.16, and 14.46 days for stages 1, 2, and 3, respectively. Twenty-five risk factors were associated with AKI. Meta-analysis of randomized controlled trials revealed that individualized blood pressure target management significantly reduced AKI incidence (RR, 0.67; 95% CI: 0.52-0.88).

conclusionsAKI remains a common and important complication after abdominal surgery, with severity showing a graded association with mortality and hospital stay. Individualized blood pressure management demonstrates promise in AKI prevention. REGISTRATION: PROSPERO CRD42022304083.

Indexed as

AbdomenAcute Kidney InjuryPostoperative ComplicationsHumansIncidenceRisk Factorsabdominal surgeryAcute kidney injuryincidencerisk factorsystematic review

Identifiers

PMID40819346
PMCPMC12360056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.