Evidence map›Paper›PMID 40819317›Full record

ArticleClinical and experimental nephrology2025

Ankle-brachial index trajectory before death in patients receiving maintenance hemodialysis.

Sachi Yamabe, Manae Harada, Yuta Suzuki, Naoyoshi Aoyama, Takaaki Watanabe, Narumi Fukuzaki, Tetsuo Shoji, Atsuhiko Matsunaga

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Article in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Sachi Yamabe *Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan.
Manae Harada *Department of Rehabilitation, Sagami Circulatory Organ Clinic, Sagamihara, Kanagawa, Japan.
Yuta SuzukiCenter for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Wako, Saitama, Japan.
Naoyoshi AoyamaDepartment of General Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Takaaki WatanabeFaculty of Health Sciences, University of Tokyo Health Sciences, Tama, Tokyo, Japan.
Narumi FukuzakiDepartment of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan.
Tetsuo ShojiDepartment of Vascular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Osaka, Japan.
Atsuhiko MatsunagaDepartment of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan. atsuhikonet@gmail.com.ORCID http://orcid.org/0000-0003-0190-707X

Funding

Japan Society for the Promotion of Science 19K11372
6 · The paper itself

Abstract

backgroundThe trajectory of the ankle-brachial index (ABI) over time in relation to death has not been fully described in patients undergoing hemodialysis. We modeled ABI trajectory pattern before death in patients undergoing maintenance hemodialysis.

methodsPatients undergoing hemodialysis in a dialysis facility were retrospectively enrolled and categorized into two groups, deceased and surviving groups, based on their status at the end of the observation period. Linear mixed-effect model and a backward timescale from the year of death or study end date were used to compare ABI trajectory between the deceased and surviving groups during the observation period.

resultsA total of 442 patients (median age, 65 years; 60.2%, men) were included. During the observation period (median, 5.3 years; maximum, 8.5 years), 130 deaths were observed. Differences in ABI between the deceased and survivors were detected in the early stages (difference at 7 years before death, 0.08; p = 0.01), with the differences between these groups becoming more pronounced at 1 year before death (difference at 1 year before death, 0.11; p < 0.001).

conclusionsDifferences in ABI trajectory between the deceased and survivors were detected from the early stages to just before death.

Indexed as

Ankle Brachial IndexKidney Failure, ChronicPeripheral Arterial DiseaseRenal DialysisAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsTime FactorsAnkle–brachial indexHemodialysisMortalityTrajectory

Identifiers

PMID40819317

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