ArticleScientific data2025
High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome.
Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- A geometry aware framework enhances noninvasive mapping of whole human brain dynamics.Nature biomedical engineering · 2026Article
- Quantitative electroencephalography as a next-generation tool in neurodiagnostics: significance, clinical applications, and practical interpretative frameworks.Frontiers in neuroscience · 2026Review
- High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome.Scientific data · 2025Article
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Authors and funding
12 authors.
Funding
Abstract
Electroencephalographic source localisation (ESL) of interictal epileptiform discharges is a valuable tool for presurgical evaluation of pharmacoresistant focal epilepsy. Various forward models, inverse solutions algorithms, and software packages have been published. However, clinical validation studies are based on heterogenous end points and study cohorts. To allow comparison of different interictal ESL methods within one standardised dataset, we provide deidentified clinical data of 44 well-characterised patients with pharmacoresistant focal epilepsy and a first resective surgery, validated by 12-month postsurgical outcome. Thirty patients had favourable outcomes, including 28 with complete seizure freedom, indicating that the epileptogenic zone was correctly estimated. For each patient, pre-processed individual structural MRI, 257-channel EEG averages of homologous discharges, postsurgical structural neuroimaging, and detailed clinical and technical information are given. In patients with favourable outcomes, source maxima of averaged discharges were <10 mm remote from the resection in 67% and within a sublobe affected by the surgery in 83%. Future validation studies of new ESL approaches can be compared to this benchmark.
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Registered trials
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