Evidence map›Paper›PMID 40819125›Full record

ArticleNature communications2025

Biosilica nanoparticulate scavengers for the therapy of hepatic ischemia-reperfusion injury in preclinical models.

Bingxin Zhou, Xuchun Chen, Renyu Ding, Zhongyun Bi, Tongyi Zhao, Ruilin Zhou, Miao Xu, Jiawen Li, Xinrui Jiang, Heran Li

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingxin Zhou *School of Pharmacy, China Medical University, Shenyang, China.
Xuchun Chen *Department of Organ Transplantation and Hepatobiliary, The First Hospital of China Medical University, Shenyang, China.
Renyu Ding *Department of Intensive Care Unit, The First Hospital of China Medical University, Shenyang, China.
Zhongyun Bi *Department of Intensive Care Unit, The First Hospital of China Medical University, Shenyang, China.
Tongyi ZhaoSchool of Pharmacy, China Medical University, Shenyang, China.
Ruilin ZhouSchool of Pharmacy, China Medical University, Shenyang, China.
Miao XuSchool of Pharmacy, China Medical University, Shenyang, China.
Jiawen LiSchool of Pharmacy, China Medical University, Shenyang, China.
Xinrui JiangSchool of Pharmacy, China Medical University, Shenyang, China.
Heran LiSchool of Pharmacy, China Medical University, Shenyang, China. liheranmm@163.com.ORCID http://orcid.org/0000-0003-2876-1525

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82172174National Natural Science Foundation of China (National Science Foundation of China) 82472136
6 · The paper itself

Abstract

Hepatic ischemia-reperfusion injury (IRI), involving intracellular Ca

Indexed as

LiverNanoparticlesReperfusion InjurySilicon DioxideAnimalsArginineCalciumCell-Free Nucleic AcidsDisease Models, AnimalHumansLiver TransplantationMaleMyeloid Differentiation Factor 88NF-kappa BNitric OxideOxidative StressArginineCalciumCell-Free Nucleic AcidsMyeloid Differentiation Factor 88NF-kappa BNitric OxidePolyethyleneimineReactive Oxygen SpeciesSilicon DioxideToll-Like Receptor 9

Identifiers

PMID40819125
PMCPMC12357891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.