Evidence map›Paper›PMID 40819119›Full record

ArticleNPJ digital medicine2025

AI-assisted multi-modal information for the screening of depression: a systematic review and meta-analysis.

Luyao Wang, Chenhan Wang, Chenyang Li, Toshiya Murai, Yicai Bai, Ziyan Song, Shuoyan Zhang, Qi Zhang, Yu Huang, Xiaoying Bi and 1 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Rethinking the prediction and prevention of dropout in digital mental health.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luyao Wang *Institute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Chenhan Wang *Institute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Chenyang LiInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Toshiya MuraiDepartment of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yicai BaiInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Ziyan SongInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Shuoyan ZhangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Qi ZhangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Yu HuangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China.
Xiaoying BiDepartment of Neurology, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China.
Jiehui JiangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, Shanghai, China. jiangjiehui@shu.edu.cn.

Funding

National Natural Science Foundation of China No. 62376150Science and Technology Innovation 2030 - Major Projects 2022ZD021600Shanghai Industrial Collaborative Innovation Project No. XTCX KJ-2023-37
6 · The paper itself

Abstract

Depression is a prevalent and costly mental disorder across all ages. Artificial intelligence (AI)-assisted physiological and behavioral information-such as electroencephalography (EEG), eye movement, video or audio monitoring, and gait analysis-offers a promising tool for depression screening. We systematically reviewed the classification performance of these AI-assisted measures in depression screening. A comprehensive literature search was conducted in Google Scholar, Web of Science, and IEEE Xplore, with the search date up to June 7, 2025. The reported AUC values are pooled estimates calculated from all results of eligible studies. AI-assisted multi-modal methods achieved a pooled AUC of 0.95 (95% CI: 0.92-0.96), outperforming uni-modal methods (pooled AUC: 0.84-0.92). Subgroup analysis indicated deep learning models showed higher performance, with an AUC of 0.95 (95% CI: 0.93-0.97). These findings highlight the potential of AI-based multi-modal information in depression screening and emphasize the need to establish standardized databases and improve research design.

Identifiers

PMID40819119
PMCPMC12357865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.