ArticleScientific reports2025
Declawing in Cat is associated with neuroplastic sensitization and long-term painful afflictions.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Green light exposure reduces central sensitization in cats with osteoarthritis-associated somatosensory impairment.iScience · 2026Article
- Somatosensory and visual evoked potentials and brainstem auditory evoked responses in osteoarthritic cats with chronic pain - a comparative study.Frontiers in veterinary science · 2026Article
- Translational validity of quantitative sensory testing in chronic pain neuro-sensitization: guide of use and interpretation in osteoarthritis animal models.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
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Authors and funding
12 authors.
Funding
Abstract
Declawing of pet cats is widely believed to cause chronic pain and negatively impact animal welfare, leading to bans in many jurisdictions. However, little is known on how post-declaw pain develops and affects feline well-being. Existing data often fail to account for other sources of chronic pain, such as osteoarthritis (OA), which affects most aging cats. Here, the aim was to distinguish chronic post-declaw pain from OA-related pain. A secondary analysis of eight studies on feline OA was conducted, comparing somatosensory, biomechanical and functional assessments between healthy control cats, declawed OA (DOA) cats, and non-declawed OA (NDOA) cats. DOA cats exhibited significant somatosensory alterations (hyperalgesia and allodynia) and greater biomechanical (worse in heavier cats) and functional impairments, compared to NDOA cats. The alterations were not dependent on the number of declawed paws (two forelimbs vs. four paws). This alarming phenotype was associated with objective nervous conduction abnormalities indicative of worsened axonopathy in DOA cats. Our findings highlight the impact of chronic post-declaw pain and support the need to develop therapeutic strategies to alleviate chronic pain in DOA cats and highlights the pertinence of establishing a global ban of this elective procedure.
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