ArticleImplementation science : IS2025
The Consolidated Framework for Implementation Research (CFIR) User Guide: a five-step guide for conducting implementation research using the framework.
Article in Implementation science : IS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620730 (PrEP-LANA), which is not on this map. Cited by 120 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PrEP-LANA (Pre-exposure Prophylaxis- Long-acting Novel Antiviral Agent)
Who cites it
120 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Implementation of Total Body Photography for Skin Cancer Early Detection: A Systematic Review.International journal of dermatology · 2026Pooled it
- Healthcare provider experiences integrating mental illness screening and management into hypertension care: qualitative systematic review.Health promotion international · 2026Pooled it
- Contextual factors influencing the integration of physical activity policy, systems, and environmental interventions in the cooperative extension system: a systematic review.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- The Effect of Education on Evidence-Based Practice Implementation Among Nurse Leaders: A Mixed-Methods Systematic Review.International nursing review · 2026Pooled it
- Impact of Cross-Sectoral Video Consultation on Perceived Care Coordination and Information Satisfaction in Cancer Care: Randomized Controlled Trial.JMIR formative research · 2025Trial
- Integrating mathematical modelling and artificial intelligence to combat emerging viral syndemics: A systematic review.New microbes and new infections · 2026Review
- Implementation gap in prehospital termination-of-resuscitation policies for out-of-hospital cardiac arrest with do-not-attempt-cardiopulmonary-resuscitation wishes in Japan: a nationwide survey.Resuscitation plus · 2026Article
- Adolescents' and parents' perspectives on addressing adverse childhood experiences in school-based health centers.Pediatric research · 2026Article
- Implementation determinants and outcomes of artificial intelligence in surgical healthcare: a systematic review protocol.BMJ open · 2026Article
- Hearing Loss Prevention Training for Spanish-Speaking Farmworkers: Protocol for a Community-Engaged Hybrid Type 1 Pilot Study.JMIR research protocols · 2026Article
- Implementing School-Associated Vaccination Events in Colorado Public Schools: A Statewide Survey of Nurses.The Journal of school health · 2026Article
- NIH Investment in HIV and Implementation Science.Journal of the International AIDS Society · 2026Article
- Implementing Telemedicine for Neonatal Care: Tutorial on a Practical Toolkit Based on Multinational Experience.Journal of medical Internet research · 2026Article
- Facilitators and barriers to patient and public involvement in developing learning health systems within community health services: ascoping review.Research involvement and engagement · 2026Review
- Community caregivers and innovative financing: a qualitative analysis of Thailand's Ubolratana Hospital model using the consolidated framework for implementation research.Health policy and planning · 2026Article
- Barriers to Implementing Medical-Legal Partnerships for Survivors of Intimate Partner Violence: Qualitative Perspectives from the Veterans Health Administration.Journal of general internal medicine · 2026Article
- A Multiphase Implementation of Ring Treatment: A Community-Engaged Control Program for T. Solium taeniasis/cysticercosis in Northern Peru.Research square · 2026Article
- Operational scholarship in emergency medicine: aligning purpose, evaluation, and dissemination.CJEM · 2026Article
- Utilizing the CFIR to Evaluate Rural COVID-19 Vaccine Uptake: Extension Personnel Perspectives.Vaccines · 2026Article
- Perceived Healthcare Interventions and Clinical Strategies Against Dating Violence: A Qualitative Exploration of Expert and Nursing Perspectives.Nursing reports (Pavia, Italy) · 2026Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundThe Consolidated Framework for Implementation Research (CFIR) is a determinant framework that includes constructs from many implementation theories, models, and frameworks; it is used to predict or explain barriers and facilitators to implementation success. CFIR is among the most widely applied implementation science frameworks, and after 15 years of use in the field, the framework was updated based on user feedback obtained via literature review and survey. Dissemination of the updated CFIR and accompanying outcomes addendum resulted in hundreds of requests from users for further guidance in applying the framework. In addition, observations of potential and actual misuse of CFIR in grant reviews and published manuscripts were the catalyst for the development of this user guide. As a result, the objective of this article is to provide a user guide and essential tools and templates for using CFIR in implementation research.
methodsThis user guide was generated from the combined wisdom and experience of the CFIR Leadership Team, which includes the lead developers of the original and updated CFIR (LJD, CMR), and has collectively used CFIR in more than 50 projects. The five steps as well as the tools and templates were finalized via consensus discussions.
resultsThe five steps below guide users through an entire research project using CFIR and include 1) Study Design; 2) Data Collection; 3) Data Analysis; 4) Data Interpretation; and 5) Knowledge Dissemination. In addition, the article provides a Frequently Asked Questions (FAQs) section based on user queries and six tools and templates: 1) CFIR Construct Example Questions; 2) CFIR Construct Coding Guidelines; 3) Inner Setting Memo Template; 4) CFIR Construct Rating Guidelines; 5) CFIR Construct x Inner Setting Matrix Template; and 6) CFIR Implementation Research Worksheet.
conclusionThis user guide details how to use CFIR in implementation research, from the design of the study through dissemination of findings, answers frequently asked questions, and offers essential tools and templates. We hope this guidance will facilitate appropriate and consistent application of the framework as well as generate feedback and critique to advance the field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.