Evidence map›Paper›PMID 40818983›Full record

ReviewNPJ microgravity2025

Critical investments in bioregenerative life support systems for bioastronautics and sustainable lunar exploration.

D Marshall Porterfield, Dana Tulodziecki, Raymond Wheeler, Mai'a K Davis Cross, Oscar Monje, Lynn J Rothschild, Richard J Barker, Hansjorg Schwertz, Steven Collicott, Som Dutta

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Space-flown spearmint (Frontiers in plant science · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

D Marshall PorterfieldDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, USA. porterf@purdue.edu.
Dana TulodzieckiPurdue Policy Research Institute, Purdue University, West Lafayette, IN, USA.
Raymond WheelerNASA Kennedy Space Center, Cape Canaveral, FL, USA.
Mai'a K Davis CrossDepartment of Political Science, Northeastern University, Boston, MA, USA.
Oscar MonjeAir Revitalization Laboratory, Aetos Systems, Kennedy Space Center, Cape Canaveral, FL, USA.
Lynn J RothschildNASA Ames Research Center, Planetary Systems Branch, Moffett Field, CA, USA.
Richard J BarkerDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, USA.
Hansjorg SchwertzMolecular Medicine Program and Division of Occupational Medicine, University of Utah, Salt Lake City, UT, USA.
Steven CollicottAerospace and Aeronautical Engineering, Purdue University, West Lafayette, IN, USA.
Som DuttaDepartment of Mechanical and Aerospace Engineering, Utah State University, Logan, UT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NASA and the CNSA have both released plans for lunar human exploration. This paper reviews those plans through the lens of strategic capability development. It examines the history of NASA's development of bioregenerative space habitation systems and shows how past research and policy decisions, including funding cuts and program discontinuations, have led to critical gaps in current NASA capabilities. These gaps pose a strategic risk to US leadership in human space exploration that must be addressed urgently to sustain international competitiveness. It concludes with recommendations for program investments crucial for the deployment of mature bioregenerative technologies in the coming decade.

Identifiers

PMID40818983
PMCPMC12357894

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.