Evidence map›Paper›PMID 40817940›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2026

Early parkinson's disease: levodopa requirements are associated with the striatal DaT-uptake.

Katarina Rukavina, Nicola Mulholland, Ben Corcoran, Magdalena Krbot Skoric, Silvia Rota, Alexandra Rizos, K Ray Chaudhuri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katarina RukavinaMovement Disorders Hospital Beelitz, Str. Nach Fichtenwalde 16, 14547, Beelitz-Heilstätten, Germany. rukavina.kk@gmail.com.ORCID http://orcid.org/0000-0002-8744-5058
Nicola MulhollandDepartment of Nuclear Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Ben CorcoranDepartment of Nuclear Medicine, Barts Health NHS Trust, London, UK.
Magdalena Krbot SkoricDepartment of Neurology, University Hospital Center Zagreb, Zagreb, Croatia.
Silvia RotaParkinson Foundation Centre of Excellence, King's College Hospital, London, UK.
Alexandra RizosParkinson Foundation Centre of Excellence, King's College Hospital, London, UK.
K Ray ChaudhuriParkinson Foundation Centre of Excellence, King's College Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine driven by clinical biomarkers is the state-of-art management approach for Parkinson's disease (PD). Whether pattern of striatal dopaminergic deficiency (demonstrated by single-photon emission CT (SPECT) scanning with

Indexed as

Antiparkinson AgentsCorpus StriatumDopamine Plasma Membrane Transport ProteinsLevodopaParkinson DiseaseAgedCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedNortropanesTomography, Emission-Computed, Single-PhotonAntiparkinson AgentsDopamine Plasma Membrane Transport ProteinsioflupaneLevodopaNortropanesClinical biomarkersLevodopa requirementsPersonalized medicineStriatal dopaminergic deficiency

Identifiers

PMID40817940
PMCPMC12827315

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.