Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Longitudinal changes in delirium motor subtypes among patients with advanced cancer in inpatient hospice and palliative care units: A secondary analysis of a multicenter cohort study.
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe stability of delirium motor subtypes in palliative care is unknown. We examined the longitudinal changes in delirium motor subtypes during palliative care unit stay.
methodsWe performed a secondary analysis of a multicenter observational study involving patients with advanced cancer. We assessed delirium, its motor subtypes, and symptoms including agitation (Memorial Delirium Assessment Scale [MDAS] item 9) and communication capacity (Communication Capacity Scale [CCS] item 4) at admission (T0), on the day of Palliative Performance Scale decline to 20 (T1, immediately before death), and daily until death.
resultsWe obtained 9,251 delirium assessments from 1,633 patients: 31% experienced hypoactive delirium without hyperactive delirium and 35% experienced hyperactive or mixed delirium during their stay. As for stability, 57% of patients with hypoactive delirium and 57% of those with hyperactive or mixed delirium at T0 remained in the same subtype until death. Further, 17% of patients with hypoactive delirium at T0 developed hyperactive or mixed delirium during their stay. Moreover, 47% of patients assessed at both T0 and T1 had a CCS item 4 < 3 (maintained communication capacity) and MDAS item 9 < 2 (no moderate-to-severe agitation) at T1. Patients with delirium (hyperactive, mixed, or hypoactive) at T0 were less likely to maintain communication capacity without moderate-to-severe agitation at T1 than patients without delirium at T0, after adjusting for covariates.
conclusionConsidering the stability of delirium motor subtypes and the difficulty in balancing comfort with communication in palliative care, individualized delirium management goals should be discussed with caregivers.
Indexed as
Identifiers
40817935What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.