Evidence map›Paper›PMID 40817722›Full record

ArticleNeural regeneration research2026

Identification of a natively resilient but poorly regenerating retinal ganglion cell type in the G protein-coupled receptor 88-Cre transgenic mouse.

Allison L Hall, Christopher Zhao, Sean McCracken, Minglei Zhao, Zelun Wang, Andrea Santeford, Rajendra S Apte, Philip R Williams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Allison L HallJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Christopher ZhaoJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Sean McCrackenJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Minglei ZhaoJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Zelun WangJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Andrea SantefordJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Rajendra S ApteJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Philip R WilliamsJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-4813-8925

Funding

NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8M
WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Steven Bassnett · 1985 to 2026
$18.4M
Research Training Program in the Vision SciencesT32EY013360 · NEI · WASHINGTON UNIVERSITY · PI SHIMING CHEN, Daniel Kerschensteiner · 2000 to 2026
$5.6M
Activity-related mechanisms of selective retinal ganglion cell resilience and axon regenerationR01EY036111 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Nicholas Minh Abell Tran · 2024 to 2026
$2.2M
Identifying and leveraging strategies of inherently resilient retinal neurons to treat degenerationR01EY032908 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 2022 to 2026
$1.9M
Kinase regulators of retinal ganglion cell survival and axon regenerationR01EY035684 · NEI · BOSTON CHILDREN'S HOSPITAL · PI ZHIGANG HE, Philip Raymond Williams · 2024 to 2026
$1.9M
NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY032908NEI NIH HHS R01 EY035684NEI NIH HHS R01 EY036111NEI NIH HHS T32 EY013360NIGMS NIH HHS T32 GM007200
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

axon regenerationG protein-coupled receptorneuroprotectionoptic nerve injuryretinaretinal ganglion cells

Identifiers

PMID40817722
PMCPMC13378955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.