Evidence map›Paper›PMID 40817666›Full record

ArticleBiomarkers in medicine2025

Prognostic impact of Naples prognostic score on long-term mortality in non-ST-elevation myocardial infarction.

Berhan Keskin, Aykun Hakgor, Fatih Erkam Olgun, Ahmet Berk Duman, Beytullah Cakal, Seda Tanyeri, Barkın Kultursay, Canan Elif Yildiz, Emir Dervis, Ibrahim Oguz Karaca and 1 more

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Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Berhan KeskinDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.
Aykun HakgorDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.
Fatih Erkam OlgunDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.
Ahmet Berk DumanDepartment of Cardiology, Kocaeli City Hospital, Kocaeli, Türkiye.
Beytullah CakalDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.
Seda TanyeriDepartment of Cardiology, Kosuyolu Heart and Research Hospital, İstanbul, Türkiye.
Barkın KultursayDeparment of Cardiology, Tunceli State Hospital, Tunceli, Türkiye.
Canan Elif YildizDepartment of Cardiology, Yeditepe University Hospital, Istanbul, Türkiye.
Emir DervisMedipol Bahcelievler Hospital, Department of Cardiology, Istanbul Medipol University, Istanbul, Türkiye.
Ibrahim Oguz KaracaDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.
Bilal BoztosunDepartment of Cardiology, Istanbul Medipol University, Medipol Mega University Hospital, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Naples Prognostic Score (NPS) is a composite index of inflammation and nutritional status. This study aimed to evaluate the prognostic value of NPS for long-term all-cause mortality in non-ST-elevation myocardial infarction (NSTEMI).

methodsIn this study, 396 consecutive NSTEMI patients who underwent coronary angiography/percutaneous coronary intervention between 1 August 2023, and 31 July 2024, were included. Patients were stratified into low (NPS: 0-1), intermediate (NPS: 2), and high (NPS: 3-4) risk groups. Median follow-up was 433 days. Univariate logistic regression identified predictors of longterm mortality. These were then entered into LASSOpenalized logistic regression for variable selection. Multivariate Cox proportional hazards models assessed the independent predictors of long-term mortality, adjusting for SYNTAX score, hemoglobin, sodium, age, and left ventricular ejection fraction (LVEF).

resultsHigh-risk NPS patients (

conclusionIn NSTEMI patients, NPS independently predicts long-term all-cause mortality beyond traditional risk markers and outperforms isolated inflammatory indices such as NLR and CRP.

Indexed as

Non-ST Elevated Myocardial InfarctionAgedBiomarkersC-Reactive ProteinFemaleHumansInflammationMaleMiddle AgedPercutaneous Coronary InterventionPrognosisProportional Hazards ModelsRisk FactorsBiomarkersC-Reactive Proteincoronary artery diseaseinflammationmalnutritionNaples prognostic scoreNon-ST-elevation myocardial infarction

Identifiers

PMID40817666
PMCPMC12481722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.